General Considerations in Dosage Forms


Prior to formulation some physico chemical properties are characterized. Chemical properties include structure, form and reactivity. Physical properties include particle size, melting point and solubility. In case of some drugs biological properties are also characterized. Age and sex of the patient also play a major role in dosage design. The others factors are Solubility, Buffer capacity and partition coefficient.


  • Physical and chemicals considerations
  • Buffer capacity
  • Partition coeficient
  • Solubility and PH
  • The phase rule
  • Melting point depression
  • Age and sex of patient

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