Pharmaceutical Formulations

Entrepreneurs who are ready to invest and get profit by working hard in the field of pharmaceutical formulations will be happy by attending this meeting and make their way a successful one by meeting intellectuals and experts who can make their investment worthwhile. This platform will be the best one to make a shape of your business.Liquid dosage forms are prepared: a) by dissolving the active drug substance in an aqueous or non- aqueous (e.g. glycerin, ether, alcohol) solvent b) By suspending the drug in appropriate medium or c) By incorporating the drug substance into an oil or water phase. Ex: Suspension, Emulsion, Syrups, Elixers.

Pharma industries are showing increased confidence in the growth of manufacturing in the market. This turn around in the market is due to the potential which is being driven by concerns of quality in some Asian markets and a marketed shift in the drug development. The primary reason behind this is an increased regulatory confidence in the standards of manufacturing.Liquid dosage forms are prepared: a) by dissolving the active drug substance in an aqueous or non- aqueous (e.g. glycerin, ether, alcohol) solvent b) By suspending the drug in appropriate medium or c) By incorporating the drug substance into an oil or water phase. Ex: Suspension, Emulsion, Syrups, Elixers.The primary reason behind this is an increased regulatory confidence in the standards of manufacturing

Regulatory affairs are a new profession which is developed by the governments to protect public health. The main aim is controlling the safety and efficacy of products in areas including pharmaceuticals, veterinary medicines, medical devices, pesticides, agrochemicals and cosmetics. Regulatory affairs also have a very specific meaning within the healthcare industries.

Pharmacists can play a role helping patients with chronic diseases have better medication at correct time and get good clinical outcomes.  They play a key role in immunization services and identifying vaccine candidates. They Participate and maintain a significant role in multidisciplinary patient care rounds. Patients often make their own decisions about managing their medications. Pharmacists could usefully serve as patient advocates, providing informationThe primary reason behind this is an increased regulatory confidence in the standards of manufacturingthat permits patients to assess risk and enhance their autonomy.

Targeted drug delivery sometimes called smart drug delivery is a method of delivering medication to a patient in a manner that increases the concentration of the medication in some parts of the body relative to other parts in the meantime reduce side effects/toxicity of payloads which are key factors for improving patient compliance.The primary reason behind this is an increased regulatory confidence in the standards of manufacturing

The drug product manufacturing facility is designed to produce injectable in syringes or vials in Grade A environment. Industries strive to improve product quality in today’s competitive environment and as well reduce the production cost.

Pharmaceutical analysis is a branch of practical chemistry that involves a series of process for qualification, purification, identification and determination of a substance, separation of the components of a solution or mixture, or determination of structure of chemical compounds. The sample to be analysed is called as analyte.

Drug design, also known as rational drug design, is the inventive process of finding new medications based on the knowledge of a biological target. Drug design defines the design of molecules that are complementary in shape and charge to the bimolecular target with which they interact and therefore will bind to it. Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.During this process different properties are checked to see whether the drug is non-toxic to living system. Drug design defines the design of molecules that are complementary in shape and charge to the bimolecular target.different properties are checked to see whether the drug is non-toxic to living system.

Pharmaceutical formulation is defined as the process in which different chemical substances are combined to produce a final medicinal product. The formulation studies involve developing a preparation of drug acceptable for patient. Formulation is the word often used in a way that includes dosage form. Formulation studies consider factors such as solubility, particle size, polymorphism and pH as all of these can influence bioavailability and hence the activity of a drug.

The drug subjected to drug development undergoes number of trials and are screened at different stages to produce a final potent drug for the treatment of various diseases. During this process different properties are checked to see whether the drug is non-toxic to living system and is therapeutic or not. Using suitable excipients and technological preparations the active substances are formulated into final dosage form. The final product is the Actual composition of preparation, manufacturing specification.The primary reason behind this is an increased regulatory confidence in the standards of manufacturing.During this process different properties are checked to see whether the drug is non-toxic to living system.

Prior to formulation some physico chemical properties are characterized. Chemical properties include structure, form and reactivity. Physical properties include particle size, melting point and solubility. In case of some drugs biological properties are also characterized. Age and sex of the patient also play a major role in dosage design. The others factors are Solubility, Buffer capacity and partition coefficient.The primary reason behind this is an increased regulatory confidence in the standards of manufacturing

“Novel Drug delivery System (NDDS) refers to the formulations, systems and technologies for transporting a pharmaceutical compound in the body as it is needed to safely achieve its desired therapeutic effects. Drug delivery systems (DDS), are based on approaches that are interdisciplinary and that combine pharmaceutics, bio conjugate chemistry, and molecular biology.

Formulations are classified into two types: based on Route of administration and Physical form. Based on route of administration they are classified as Oral, Topical, Rectal, Parenteral, Vaginal, Inhaled, Ophthalmic and octic

Gaseous dosage forms are packed in a container which gets released upon applying pressure. The gas inside contains therapeutically active medicaments. The containers have valve systems with continuous or limited delivery. They are used for topical application on skin and as local application into nose and mouth.

Liquid dosage forms are essential pharmaceutical products which involves a mixture of active drug components and nondrug components (excipients). Liquid dosage forms are prepared: a) by dissolving the active drug substance in an aqueous or non- aqueous (e.g. glycerin, ether, alcohol) solvent b) By suspending the drug in appropriate medium or c) By incorporating the drug substance into an oil or water phase. Ex: Suspension, Emulsion, Syrups, Elixers.

Semi solid dosage forms are the products when applied to the skin treat a pathological condition and protects from other harmful environment. They are smooth,non-staining and get miscible with skin secretions. Creams, Gels, Pastes etc. are the examples.

Solid dosage formulations are important dosage forms in pharmaceuticals. e.g. tablets, capsules, granules, sachets, reconstitutable powders, powders, dry powder inhalers and chewables. Solid dosage form contains unit dose of one or more medicament. Excipients include Binders, Glidants, Sweeteners etc.